MDACC ORION

 

Please include the following acknowledgement in research publications supported by the core: "Supported by the NIH/NCI under award number P30 CA016672 and used the ORION core".

Overview of Services

The purpose of our core is to provide state-of-the-art immunoprofiling services to MDACC investigators as well as local investigators. Our services range from single service instrument use to entire project design and analysis. Researchers and Investigators will need to provide the samples for analysis. Samples can be stored short-term prior to assessment.

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Services:

• Clinical trial immune monitoring
• Custom panel design for assays
• Guidance on language and funding for grant applications
• Data analysis
• Single assay instrument use 

Equipment and Technology:

• Luminex 200 (assisted only)
  
• MSD QuickPlex SQ120 (assisted and unassisted)
  
• CTL ELISPOT analyzer - Immunospot S6 MICRO (assisted and unassisted)
  
• Flow Cytometry of up to 18 colors (assisted only) 

Leadership

Cara Haymaker, Ph.D. | Director | (713) 792-1458 | chaymaker@mdanderson.org 

Ignacio Wistuba, M.D. | Co-Director 

Location and hours of operation

Location	Hours
2SCRB2.3203, 7455 Fannin Street    Houston, TX 77054	Monday-Friday  8:00am-5:00pm

Links and Resources 

Luminex

Kit Vendors:

• Invitrogen ProcartaPlex Immunoassays
• ProcartaPlex Analyst Software (free download, Windows or Mac)

Sales representative: Nick Tardi | Nick.Tardi@thermofisher.com

• Bio-Rad Bio-Plex Assay Builder

Sales representative: Christof Straub | christof_straub@bio-rad.com

• Millipore Milliplex Analyte Finder or Design Your Own Kit

Sales representative: Melissa Muller | melissa.muller@emdmillipore.com

Templates and SOPs:

• Luminex_PlateLayout_Template
• Cell Culture Supernatant Preparation for Luminex Soluble Factor Analysis
• <coming soon: Tissue Lysate Preparation for Luminex Soluble Factor Analysis>

 

MSD:

Kit Vendor:

• Meso Scale Discovery
• Assay/Analyte List
• Custom Assay Designer
• Discovery Workbench Analysis Software (free download, Windows only)

Sales representative: Katlin Holmes | kholmes@mesoscale.com

Templates and SOPs:

• MSD_PlateLayout_Template
• MSD QuickPlex SQ 120 QuickStartGuide

 

ELISPOT Kit Vendors:

• CTL ImmunoSpot
• Mabtech

 

CCSG Shared Resource Cores:

• Tissue Biospecimen & Pathology Resource (ITB)
• Research Histology Core Laboratory

 

Longitudinal Patient Collections for Clinical Trials:

• APOLLO Research Platform

Contacts

Name	Role	Phone	Email	Location
ORION Core lab	Oncology Research and Immunomonitoring	713-792-1458	ORIONCore@mdanderson.org	7455 Fannin St, 2SCR2.3203, Houston, TX 77054

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