Please Acknowledge

In order to continue obtaining Core support in a challenging environment, it is crucial that our users acknowledge the following support in all publications (see following text).  Thank you!

“This work was supported in part by the U.T.-M D Anderson Cancer Center and NIH grant number 1S10OD012304-01.”

Overview of Services

Mission.  The mission of the Proteomics Core Facility is to provide the research community with cutting-edge expertise and services for sensitive, precise, and accurate identification and measurement of proteins using mass spectrometry-based technologies.

SERVICES

Proteomics:

• Protein Identification: High sensitivity (silver stain OK), 1000 or more proteins may be indentifiable. There are two options, one for lower-complexity samples, and one for higher-complexity samples that will entail a longer run.
• Molecular Weight Determination: Check the MW of your peptide or molecule.  Small proteins may be measured if enough clean protein is available (larger proteins are less reliable), proteins are better analyzed by LC-MS (below). 
• Quantitative Protein Analysis:  Using stable isotope methods, iTRAQ, TMT, SILAC, etc. For SRM/MRM methods on our tandem quadrupole MS, please inquire. Quantitative Protein Profiling using MRM, HRM or DIA (Swath-like) methods, with or without reference peptides (lists available, custom lists can be built).
• Posttranslational Modification Analysis:  Phosphorylation, acetylation, methylation, ubiquitination, etc. Please inquire for more detailed information.
• LC or LC-MS Analysis:  Size exclusion chromatography and simple RP LC-MS are common examples.  Please inquire for more detailed information and other chromatographic analyses available.

Data Analysis:

• Data Analysis: Many of the reports generated by our facility are time-consuming to assemble; we add a data analysis fee for reports that require an unusual amount of effort. Expertise includes bioinformatics, statistics, pathway analysis, and/or assistance preparing materials for manuscripts or presentations.
  

__________________________________________________________________________________________________________________________________________________________________________________________

Leadership 

Proteomic Services:

Phil Lorenzi, Ph.D., Director

Email:  PLLorenzi@mdanderson.org

713-792-9999

Location and hours of operation

Links and Resources

Our website contains additional information including an FAQ and tutorials.

1. Proteomics Core Website
2. Metabolomics Core Website

Contacts

Map

https://www.google.com/maps/place/7435+Fannin+St,+Houston,+TX+77054/@29.6946185,-95.4021514,17z/data=!3m1!4b1!4m5!3m4!1s0x8640c00edc82b849:0x2ef57e13d2575f32!8m2!3d29.6946139!4d-95.3999627