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DO NOT SUBMIT SAMPLES WITH PATIENT HEALTH INFORMATION.  This includes medical record numbers or pathology file identifiers.

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MDACC Proteomics

Please Acknowledge

In order to continue obtaining Core support in a challenging environment, it is crucial that our users acknowledge the following support in all publications (see following text).  Thank you!

 

This work was supported in part by the U.T.-M D Anderson Cancer Center and NIH grant number 1S10OD012304-01.

 

Overview of Services

Mission.  The mission of the Proteomics Core Facility is to provide the research community with cutting-edge expertise and services for sensitive, precise, and accurate identification and measurement of proteins using mass spectrometry-based technologies.

 

SERVICES

 

Proteomics:

  • Protein Identification: High sensitivity (silver stain OK), 1000 or more proteins may be indentifiable. There are two options, one for lower-complexity samples, and one for higher-complexity samples that will entail a longer run.
  • Molecular Weight Determination: Check the MW of your peptide or molecule.  Small proteins may be measured if enough clean protein is available (larger proteins are less reliable), proteins are better analyzed by LC-MS (below). 
  • Quantitative Protein Analysis:  Using stable isotope methods, iTRAQ, TMT, SILAC, etc. For SRM/MRM methods on our tandem quadrupole MS, please inquire. Quantitative Protein Profiling using MRM, HRM or DIA (Swath-like) methods, with or without reference peptides (lists available, custom lists can be built).
  • Posttranslational Modification Analysis:  Phosphorylation, acetylation, methylation, ubiquitination, etc. Please inquire for more detailed information.
  • LC or LC-MS Analysis:  Size exclusion chromatography and simple RP LC-MS are common examples.  Please inquire for more detailed information and other chromatographic analyses available.

 

 

 

Data Analysis:

  • Data Analysis: Many of the reports generated by our facility are time-consuming to assemble; we add a data analysis fee for reports that require an unusual amount of effort. Expertise includes bioinformatics, statistics, pathway analysis, and/or assistance preparing materials for manuscripts or presentations.

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Leadership 

 

Proteomic Services:

 

  

Location and hours of operation

Hours: Location:

Sample Drop Off:

Monday - Friday

8 AM - 5 PM

By appointment only!                        

Lab: 2SCR3.3217
Phil Lorenzi: 4SCR3.1032    

  

Links and Resources

Our website contains additional information including an FAQ and tutorials.

  1. Proteomics Core Website

Contacts

Name Role Phone Email Location
Sara Zanivan
Director
 
346-723-7487
 
srzanivan@mdanderson.org
 
4SCR2.1140
 

Services & Rates


Search available services: View: by category alphabetically
Proteomics, Antibody-Based (6)
Proteomics, MS-based, Label-free (2)
Proteomics, MS-based, TMT (1)
Data Analysis (2)
Equipment Usage (2)

Map


https://www.google.com/maps/place/7435+Fannin+St,+Houston,+TX+77054/@29.6946185,-95.4021514,17z/data=!3m1!4b1!4m5!3m4!1s0x8640c00edc82b849:0x2ef57e13d2575f32!8m2!3d29.6946139!4d-95.3999627