People search results may not give full user list for core and searches for users may not show. Agilent R&D is investigating as an urgent issue and updates can be found by clicking on 'Help' at the top right of your account page and on the Issue Tracking panel.


MD Anderson's core facilities are slowly returning to operations and will be at reduced capacity.  Please contact core personnel for instructions prior to submitting a request and indicate if the sample is known to be COVID-19 positive.

(hide this warning on this page)

MDACC Proteomics

Please Acknowledge

In order to continue obtaining Core support in a challenging environment, it is crucial that our users acknowledge the following support in all publications (see following text).  Thank you!


This work was supported in part by the U.T.-M D Anderson Cancer Center and NIH grant number 1S10OD012304-01.


Overview of Services

Mission.  The mission of the Proteomics Core Facility is to provide the research community with cutting-edge expertise and services for sensitive, precise, and accurate identification and measurement of proteins using mass spectrometry-based technologies.





  • Protein Identification: High sensitivity (silver stain OK), 1000 or more proteins may be indentifiable. There are two options, one for lower-complexity samples, and one for higher-complexity samples that will entail a longer run.
  • Molecular Weight Determination: Check the MW of your peptide or molecule.  Small proteins may be measured if enough clean protein is available (larger proteins are less reliable), proteins are better analyzed by LC-MS (below). 
  • Quantitative Protein Analysis:  Using stable isotope methods, iTRAQ, TMT, SILAC, etc. For SRM/MRM methods on our tandem quadrupole MS, please inquire. Quantitative Protein Profiling using MRM, HRM or DIA (Swath-like) methods, with or without reference peptides (lists available, custom lists can be built).
  • Posttranslational Modification Analysis:  Phosphorylation, acetylation, methylation, ubiquitination, etc. Please inquire for more detailed information.
  • LC or LC-MS Analysis:  Size exclusion chromatography and simple RP LC-MS are common examples.  Please inquire for more detailed information and other chromatographic analyses available.




Data Analysis:

  • Data Analysis: Many of the reports generated by our facility are time-consuming to assemble; we add a data analysis fee for reports that require an unusual amount of effort. Expertise includes bioinformatics, statistics, pathway analysis, and/or assistance preparing materials for manuscripts or presentations.






Faculty Oversight:

Dr. John Weinstein


Proteomic Services:

David Hawke, Ph.D., Director




Location and hours of operation

Hours: Location:

Sample Drop Off:

Monday - Friday

8 AM - 5 PM

By appointment only!                        

Lab: 2SCR3.3217
David Hawke: 2SCR3.3025             


Links and Resources

Our website contains additional information including an FAQ and tutorials.

  1. Proteomics Core Website
  2. Metabolomics Core Website


Name Role Phone Email Location
David Hawke, Ph.D

Services & Rates

Search available services: View: by category alphabetically
Proteomics (5)
Data Analysis (2)
Equipment Usage (1)