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xx MDACC Recombinant Antibody Production Core

Overview of Services

This Core ended 8/31/2024.  The Recombinant Antibody Production Core (RAPC) provides custom recombinant monoclonal antibodies to investigators in a rapid, high-throughput, and cost-effective manner. Our methodology overcomes many of the issues with classical methods, namely lackluster antibody reproducibility and characterization, and is particularly well suited for generating antibodies against challenging targets such as antigens with single amino acid polymorphisms and post-translational modifications. We also offer engineering of recombinant antibodies to provide enhanced features such as fluorescent or affinity tags. 

Services:

  • Recombinant Antibody Project Consultation (Feasibility, Antigen Design)
  • Recombinant Antibody Production, Purification, and Characterization
  • Recombinant Antibody Engineering
  • Hybridoma Rescue

Leadership

Kevin McBride, PhD | Core Director
kmcbride@mdanderson.org
832-750-7195

Joshua Plummer, MS | Core Operations Manager
jbplumme@mdanderson.org
832-750-7198

Monika Zelazowska, PhD | Core Scientific Manager
MAZelazowska@mdanderson.org
832-750-7199

Location and hours of operation

Hours  Location

Monday - Friday: 8am-5pm

 4SCRB 4

Links and Resources

RAPC

Contacts

Name Role Phone Email Location
Kevin McBride
Core Director
 
832-750-7195
 
kmcbride@mdanderson.org
 

 
Joshua Plummer
Core Operations Manager
 
832-750-7198
 
jbplumme@mdanderson.org
 

 
Monika Zelazowska
Core Scientific Manager
 
832-750-7199
 
MAZelazowska@mdanderson.org